CEOs from Virgin, Levi Strauss, Coca-Cola and Johnson&Johnson among others have called on the 45 countries that restrict entry, stay and residence for HIV-positive people to change their laws.
The call was made on the first day of the International AIDS conference in Washington DC on Sunday.
The conference is being held in the US for the first time in 22 years because in 2010 President Obama lifted the travel restrictions on HIV positive people visiting the US.